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Reduces oxidative stress associated with aging

The glutathione S-transferases: influence of polymorphism on cancer susceptibility IARC Sci Publ 1999 148 : 231249 Chen CL, Liu Q, Pui CH, Rivera GK, Sandlund JT, Ribeiro R, Evans WE, Relling MV

FACS staining integrins Colon (P26N) and duodenum (Duo-72) organoids were enzymatically processed to single cells and incubated with integrin component-specific antibodies, each directly conjugated to a different fluorophore

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These findings suggest that gut redox homeostasis is a key beneficiary of the restorative processes associated with sleep but that the gut may also actively mediate the systemic effects of sleep, including on longevity and aging (Vaccaro et al., 2020)