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Importantly, studies examining smokers who switched to e-cigarettes have reported improvements in blood pressure control over follow-up periods of 6 to 12 months [23, 24], suggesting that the net cardiovascular effect may depend critically on whether e-cigarette use replaces or supplements combustible cigarette smoking [25]

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7 A thorough assessment, including an intra- and extraoral examination, can identify some of the physical and oral characteristics of EDS