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These decrease over time for most researchers

Redness, itching, or mild irritation at the application site can occur, particularly during initial use or with higher concentrations

The Journal of Investigative Dermatology, 113 (3), 364368

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Nevertheless, mild and temporary reactions can occur, including: Redness Warmth at the injection site Light swelling Short-term irritation Avoid the peptide if you have a copper allergy or an active infection in the targeted area

One study investigated the safety and efficacy of 5-aminolevulinic acid (5-ALA) and glycyl-histidyl-lysine (GHK) for pattern hair loss