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Bone Density: Mouse model studies have also linked IGF-1 signaling to improvements in bone density and skeletal strength, suggesting systemic health benefits beyond just muscular development

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These signals reshape transcription through the JAK-STAT6/STAT3 pathway and induce macrophages to transition into the M2 phenotype

The development of enzyme-mimicking nanomaterials (nanozymes) with good reactive oxygen species (ROS) scavenging ability and biocompatibility is a promising way for the treatment of ROS-related inflammation