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Then, LC3-I is processed and modified by ubiquitination to membrane-bound LC3-II, which is localized in the pre-autophagosome and autophagosome

Confronted with the substantial global increase in PD prevalence and the persisting unmet clinical needs in managing both motor and non-motor symptoms, the development of multi-target therapeutic strategies is critically important

This suggests that unlike for the CM-degrading strain, DM4 plasmids do not play a role in adaptation to DCM in strain DM4

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Relationship between primary structure or spatial conformation and functional activity of antioxidant peptides from Pinctada fucata

They work best when combined with a healthy diet and regular exercise, and should be positioned as complements to lifestyle change rather than replacements for it