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Apply an appropriate amount to the area you wish to treat, following the skin texture, and gently pat to help absorption

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M2-like (or homeostatic) states help preserve neurons by removing extracellular -synuclein fibrils, releasing neurotrophic factors like BDNF (brain-derived neurotrophic factor) and GDNF (glial cell linederived neurotrophic factor), encouraging synaptic repair, boosting glutamate uptake via EAAT2, and creating anti-inflammatory cytokines like IL-10 and TGF-

4e, microbial DNA extraction from fecal content was done using ZymoBIOMICS 96 Magbead DNA Kit automated on a Tecan Fluent 480 liquid handling system

Blocked with 3% BSA for 1 h at room temperature, then incubated with rabbit polyclonal anti-GSDME (1:100, A7432, ABclonal, Wuhan, China) in 3% BSA overnight at 4 C