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Forward Mendelian randomization analysis Firstly, we used Ghodsian et al., GWAS data to perform the forward MR analysis

Ethics statement The trial was conducted in accordance with the Declaration of Helsinki (1996 revision) and under the principals of good clinical practice, as laid out in the International Conference on Harmonization document Good Clinical Practice Consolidated Guideline

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Individuals with Wilson's disease or significantly compromised skin barrier should consult a physician before use

208 Taking high doses of pyridoxine for prolonged periods results in abnormally high circulating pyridoxine levels

Newman, E