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Acting as a central amplifier of immune and metabolic stress, the injured intestine promotes the dissemination of gut-derived danger signals, inflammatory mediators, and toxic metabolites, thereby driving distant organ injury and multiple organ dysfunction

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Glutathione reductase catalyzes the reduction of GSSG to GSH by NADPH

You may use the same general area, but choose a different location to help reduce irritation and give the skin time to recover