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Bradley 2008

A 2.5 mg Tirzepatide dose on a 50 mg vial reconstituted with 1 mL of water is 5,000 mcg 50,000 mcg/mL 100 = 5 units

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However, despite being estimated to have similar extinction coefficient compared to the first charge transfer absorption (Figure 3A inset), the C159S variant is observed to only fractionally reduce to 20% and the NADPH-FAD charge transfer absorption dominates the observation of initial events in the reductive half-reaction as a result of residual NADPH