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It also binds to the G-protein coupled receptor GPR43 to increase plasma lipid utilization by controlling the activation of lipoprotein lipase (LPL) via adipose GPR43 (Miyamoto et al., 2019

Thus, it seemed interesting to look into the possible protective effect of this molecule on the effects of strenuous exercise, in which free radicals seem to be involved

Gastroenterology 161, 19241939

References for this information: Biochemistry and Cell Biology , 2019, volume 92, issue 3, pages 270-289 Biochemical Pharmacology , 2003, Volume 66, issue 8, pages 1499-1503 International Journal of Biomedical Science , 2008, volume 4, issue 2, pages 89-96 Pharmacology Review, 2010, volume 4, issue 8, pages 118-126 Antioxidants and Redox Signaling , 2013, volume 19, issue 8, pages 813-822 Nutrients , 2019, volume 11, issue 9 Biomolecules , 2015, volume 5, issue 2, pages 545-589 Aging: Oxidative Stress and Dietary Antioxidants , 2014, pages 15-22 Asian Pacific Journal of Cancer Prevention, 2014, volume 15, issue 2, pages 561-568 Clinical, Cosmetic and Investigational Dermatology , 2017, volume 10, pages 147-153 British Society for Immunology , 2020, volume 160, issue 2, pages 116-125 Harvard T.H

It plays several roles in a formula: Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products

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