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In this case, the researchers think that epigenetic markers decrease the availability of the norepinephrine transporter in POTS.[ref] Autoimmune involvement in POTS: Research shows that for some people, POTS can be due to an autoimmune attack on either the adrenergic system or the renin-angiotensin system .[ref][ref] Both systems are important in heart rate and blood flow

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[DOI: 10.1371/journal.pmed.1000100] [DOI] [PMC free article] [PubMed] [Google Scholar] Lindenbaum 1994 Lindenbaum J, Rosenberg IH, Wilson PW, Stabler SP, Allen RH

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