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Results: High polygenic risk was associated with 37% increase in uncontrolled (OR 1.37, 95% CI 1.16-1.63) and a two-fold increase in resistant risk factors (OR 2.09, 95% CI 1.77-2.48)

As a result, the activity of the electron transport chain (ETC) is hindered, decreasing ATP production during oxidative phosphorylation [8]

Beyond its proteolytic function, PR3 serves as the major autoantigen in anti-neutrophil cytoplasmic antibody-associated vasculitis, conferring special relevance in autoimmune diseases ( CatG exhibits distinctive dual biological characteristics, effectively degrading various extracellular matrix proteins while possessing significant antimicrobial activity

Bemark, M., Liberg, D

Despite their differences, these bacteria share the ability to form dental biofilmsdynamic and metabolically active structures representing a significant challenge to antibiotic therapy [15, 16]

Hyposmia, anosmia