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Furthermore, obesity alone, without asthma or other lung diseases, can exacerbate bronchial inflammation

PRP (platelet-rich plasma) provides a heterogeneous cocktail of autologous growth factors (PDGF, TGF-beta, IGF-1), but its composition varies from one draw to another

TLR-2 and TLR-9 are sensors of apoptosis in a mouse model of doxorubicin-induced acute inflammation

158,308,466,467,468,469 The pharmacological effect of PPAR activation in attenuating various forms of PH involves modulating 5-HT-induced AP-1 activity, 470 HO-1 and p21 (WAF1), 471 store-operated Ca 2+ entry, TRPC and HIF-1, 130,472,473,474,475 ERK1/2-NF-B-NOX4-H 2 O 2 signaling axis, 158,476 miRNAs, 477,478 and HUWE1/miR-98 479 pathways

Nat Rev Dis Primers (2015) 1:15017