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Aquaculture 491, 239251

Hydroxychloroquine in rheumatic autoimmune disorders and beyond

Zhao et al., 2021a

Simultaneously, catalytically produced hydrogen peroxide (H 2 O 2 ) activates the protein transient receptor potential melastatin 2 (TRPM2) ion channel, promotes calcium influx, activates macrophages, and induces systemic immune response (Fig