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This impairs cellular functions and further exacerbates mitochondrial dysfunction [58]

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Hwang HS, Kim HA

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In the study of triple-negative breast cancer (TNBC), researchers found that hybridized BLG@TPGS NPs were prepared by doping the multipath energy inhibitors berberine (BBR) and lonidamine (LND) as well as the chemotherapeutic agent garcinia cambogia (GA), which inherited the mitochondria-targeting ability of BBR and accurately accumulated in the mitochondria, then induced starvation therapy, which effectively eradicated cancer cells by coordinating the shutdown of tumor cells through the three-tendency strategy to cut off the mitochondrial respiration, glycolysis and glutamine metabolism [223]

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Moreover, we discovered GRAS cis -elements relevant to plant growth/development, comprising 02-site of having 2%, which are linked to zein metabolic responsiveness (Li et al., 2020)

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Kaempferol induces mitochondrial dysfunction and mitophagy by activating the LKB1/AMPK/MFF pathway in breast precancerous lesions

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It is commonly known to function as a powerful antioxidant and is manufactured as a medicine or supplement to prevent aging

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