glutathione s-transferas 14-3-3 ncbi Overexpression of S-Transferases in Human Diseases: Drug Targets and Therapeutic Implications Glutathione S-transferase: a versatile protein

Trapnell, C

The human skin, accounting for approximately 16% of total body weight, is the largest organ and serves as a primary barrier against environmental insults such as microbial invasion, UV radiation, and chemical or mechanical stress [217, 218]

The results were analyzed using computer imaging by observing the spread of the rats' toes, where their total spread indicated significant tendon damage

For epidermal keratin-forming cells, various extracellular stimuli (including UV light) can trigger signaling cascades associated with stress responses, the most important of which is the activation of mitogen-activated protein kinases (MAPKs)

Sources: Dimet-Wiley AL, Latham CM, Brightwell CR, et al

Further in vitro studies have shown that IAA can promote epithelial cell proliferation and enhance tight junction repair by activating the AhR/IL-22 signaling pathway, thereby counteracting LPS-induced epithelial injury and preventing LPS-driven systemic inflammation 168