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386,387 Autophagy-inducing small molecules and natural compounds Additional autophagy-inducing agents include lithium, which induces autophagy via inhibition of inositol monophosphatase and reduces tau and amyloid- aggregation in AD models, 388 and SMER28, a small-molecule enhancer of rapamycin that promotes autophagy and reduces tau and -synuclein aggregation in AD and PD models

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The initial inhibitory concentrations of gastrointestinally digested (GID) L-St were estimated to be 25.40 3.94 g/ml for HIEC-6 cells and 3.02 0.48 g/ml for CCD 841CoN cells (Table 1)

[The use of melatonin in the treatment of chronic fatigue syndrome and circadian rhythm disorders in Parkinson's disease.]

PCS often includes chronic fatigue, myalgia, and sleep disturbances, with many symptoms overlapping with CFS