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The crystal structure of HpTpx_C R A in complex with Metro displays the inhibitor reduced to its amine derivative ( Metro * ), which is fully defined in the observed electron density ( F o )calculated electron density ( F c ) map and forms an irreversible thioether bond with the C P residue (Fig

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(2011) Cocaine-induced adaptations in cellular redox balance contributes to enduring behavioral plasticity, Neuropsychopharmacolgy , 36 , 25512560