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For instance, many AD studies in this meta-analysis did not report disease severity, limiting the ability to perform subgroup analyses

The liver plays a central role in clearing acetaldehyde, a highly reactive and carcinogenic intermediate ( In addition, chronic alcohol intake shifts metabolism toward CYP2E1 because ADH becomes saturated at higher alcohol levels

M.BrightL.OldroydG.HarrisJ

Additional large scale prospective controlled studies should be conducted to evaluate the safety of coffee enema use

doi: 10.1021/bi00262a004

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