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Additionally, IF downregulated the expression of AQP4-M1 and histone deacetylase 3, reduced the AQP4-M1/M23 ratio, and increased miR-130a expression in the cortical region of APP/PS1 mice

[PUBMED Abstract] Weischer M, Heerfordt IM, Bojesen SE, et al.: CHEK2*1100delC and risk of malignant melanoma: Danish and German studies and meta-analysis

Furthermore, the newly developed xanthonic compounds were found to have a relatively low toxicity margin

Functionally, HEK293- SLC13A3 cells had a significant increase in the uptake activity of 14 C-succinate compared to HEK293- EV cells (Supplementary Fig