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Discard unused portion of an opened vial, as the formulation does not contain a preservative

The study by Neelakantan et al

The number of cells was counted using Trypan blue (Sigma, T8154) and a hemocytometer (Bright-Line), and 5 10 5 cells were plated into 24-well plates

Cells activate the Unfolded Protein Response (UPR) to restore homeostatic protein processing by clearing out the stress of accumulated misfolded proteins (adaptive arm)

Moreover, the participants must be in HoehnYahr stages IIV and show responsiveness to levodopa treatment, with a LCT improvement rate of 30%

Wang Y, Qian D, Wang X, Zhang X, Li Z, Meng X, et al