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Perturbation of the 1-carbon cycle result in folate deficiency and abnormal plasma Hcy concentrations [104, 105], which may contribute to the risk that any given mother will or will not have a child with DS

Blood samples were collected from the jugular vein before inoculation and 20 days after to quantify the activity of the glutathione peroxidase enzyme (GPx), total antioxidant capacity (TAC), and reduced glutathione (GSH)

123 , e55617 (2017)

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References 1 AlbanoG

Lowered cellular redox status increases susceptibility to oxidative stress that may lead to cell death and virus release (Raftos et al., 2007