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During periods of cellular stress, GSH can enter mitochondria through the solute carrier family 25 member 39 (SLC25A39) 10,11

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observed that a small subset of GBM tumor sections with high CDK5 and p35/p25 levels exhibited apoptotic features

Agarwal N, Lamichhane G, Gupta R, Nolan S, Bishai WR

Consistent with impaired transfer of reducing equivalents from the cytosol to mitochondria in the absence of GOT1 and GOT2, expression of LbNOX in the mitochondria had little or no effect on either the cellular NAD + /NADH ratio or proliferation (Fig