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10.1111/jnc.15519 198 JiaB.LiJ.SongY.LuoC

Deubiquitination is primarily catalyzed by DUBs, which are classified into seven families based on sequence and structural similarity: ubiquitin-specific proteases (USPs), ovarian tumor proteases (OTUs), ubiquitin c-terminal hydrolases (UCHs), Machado-Josephin domain proteases (MJDs), JAB1/MPN+/MOV34 (JAMM) domain proteases, monocyte chemoattractant protein-Induced protein (MCPIP), and a novel family of DUBs associated with ubiquitin-binding, motif Interacting with Ub-containing novel DUBs (MINDYs) ( Figure 1 To date, more than 100 DUBs have been identified (Figure 2)

10.1016/j.cell.2012.11.024 105 LuoM.ZhaoF.ChengH.SuM.WangY

Value of clinical flicker frequency and psychometric hepatic encephalopathy score in diagnosis of low grade hepatic encephalopathy

While not strictly necessary, allowing the lyophilized peptide vial to come to room temperature for a few minutes can sometimes help it dissolve more readily

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