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Weighted gene co-expression network analysis (WGCNA) identified genotype-driven, rather than treatment-driven, gene modules, highlighting distinct transcriptional architectures between WT and KO animals

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Clinical research has explored cagrilintide in combination with semaglutide in adults with overweight or obesity and type 2 diabetes, where treatment was associated with improvements in body weight and glycemic measures such as HbA1c [6]

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