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doi: 10.1093/labmed/lmz017 118 ParedesSFonsecaLRibeiroLRamosHOliveiraJCPalmaI

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One directly affects the somatotropic cells of the anterior pituitary, itself inhibiting further release of GH, whilst the other affects GH releasing hormone and somatostatin release from the hypothalamus to reduce the secretion of GH

It is imperative to elucidate the physiological alterations necessitated to establish a period of heightened sensitivity or susceptibility to disease, as well as the underlying mechanisms

10.1016/j.jpsychires.2006.04.007 116 StengelA.CoskunT.GoebelM.WangL.CraftL.Alsina-FernandezJ.et al

Diabetes Care, 41(12), 2669-2701