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Renal function tests are important, as GLP-1 receptor agonists can occasionally affect kidney function, particularly in patients with pre-existing renal impairment or those experiencing severe gastrointestinal side effects leading to dehydration

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Similarly, anyone experiencing unexplained fatigue, weakness, neurological symptoms (such as numbness, tingling or problems with balance), or difficulty losing weight despite appropriate lifestyle measures should consult their GP

8 This effect increased with duration of therapy, and patients had an unclear prophylactic supplementation response