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Proton pump inhibitors have a half life of 0.5 2 hours but they irreversibly inhibit the proton pumps; hence, their action persists for 24 48 hours. They are therefore known as 'hit and run drugs'. The hit and run SNR #129: Chris Masterjohn, PhD Glycation, Oxidative Stress & The Protective Effects of Glucose and Insulin Sigma Nutrition Glutathione 101, Part 1: Cysteine Misbehaves, But Glutathione Saves The Weston A. Price Foundation 46 Chris Masterjohn, Ph.D.: Navigating the many pathways to health and disease NAD and sirtuins, methylation, MTHFR and COMT, choline deficiency and NAFLD, TMAO, creatine, and more The Peter Glutathione Intolerance: Getting to the Bottom of It Regulatory Effects and Molecular Mechanisms of Tea and Its Active Compounds on Nonalcoholic Fatty Liver Disease Journal of Agricultural and Food Chemistry

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