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References Agnelli G, Buller HR, Cohen A, Curto M, Gallus AS, Johnson M, et al

in its approved obesity indication semaglutide 2.4 mg once weekly produced roughly 15% mean weight loss over 68 weeks in STEP 1 [5]

Importantly, the C-terminal region of this protein (residues 59197) remains mostly disordered even in the presence of 1 M kF (Crane-Robinson et al., 1976)