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10.1093/tas/txae030

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doi: 10.1172/JCI.INSIGHT.156549 224 Amylyx Pharmaceuticals Announces Interim Data From Ongoing Phase 2 HELIOS Clinical Trial Demonstrating Improvements in Pancreatic Function and Glycemic Control with AMX0035 in People with Wolfram Syndrome | Amylyx

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Such fragmentation impairs substrate and protein exchange across the mitochondrial network, compromises m and reduces coupling efficiency between electron transport and ATP synthesis