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In living organisms, the degree of oxidative damage is reflected by the level of malondialdehyde (MDA), the end product of free radical-mediated lipid peroxidation

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88 Similarly, IL-13 the T-helper type 2 cytokine and key effector of ulcerative colitis also affects intestinal epithelial cell TJ function as well as apoptosis, 89 and was recently shown to regulate claudin-2 transcription in a signal transducers and activators of transcription-dependent manner

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