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9 Tolerability, safety and regulatory considerations Preclinical investigations consistently demonstrate that luteolin is well tolerated across multiple experimental systems

10.1016/j.bios.2016.04.091 38 DanielsD

529.Zhan T, Rindtorff N, Boutros M

Nutr 27, 10311039

Zhang X, Bao G, Liu D, Yang Y, Li X, Cai G, Liu Y, Wu Y

Further downstream, HIF1 KO NSCLC cells displayed higher synthesis of the ser/gly pathway derived m + 6 AMP nucleotide, while m + 6 and m + 7 ATP synthesis was diminished, consequently showing a higher AMP/ATP ratio (Fig