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A variety of single-cell epigenome-sequencing techniques have been developed, such as single-cell sodium bisulfite sequencing for DNA methylation detection, 345 single-cell chromatin immunoprecipitation sequencing for the identification of histone modification and proteinDNA interaction, single-cell transposable accessible chromatin sequencing, and Hi-C sequencing for the evaluation of chromatin accessibility and chromosome conformational information

Mouse treatment For all experimental procedures, Tbx1 + / and WT mice were injected intraperitoneally with vB12 dissolved in PBS 20 mg/kg (stored away from light) or with PBS, twice a week for 4 wk starting at 4 wk of age

[DOI] [PMC free article] [PubMed] [Google Scholar] 70.Al-Dhuayan I.S

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