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Gandhi VV, Gandhi KA, Kumbhare LB, Goda JS, Gota V, Priyadarsini KI et al (2021) 3,3-Diselenodipropionic acid (DSePA) induces reductive stress in A549 cells triggering p53-independent apoptosis: a novel mechanism for diselenides

Upon illumination Rg increases from 42.1 (dark) to 52.2 (light), thus revealing an expansion of the protein, while I(0) remains almost unchanged (1.03 10 and 1.08 10 for dark and light state, respectively), indicating that the protein remains in its dimeric form

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Moreover, it can prevent angiogenesis, invasion, and metastasis by decreasing phosphorylation of rac1 in renal cancer cells [31]

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