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Oncotarget 2016

Just that we have very limited data on the systemic effects

The ubiquitin homologue, Bacteroides fragili s ubiquitin (BfUbb), secreted by some strains of the gut bacterium Bacteroides fragilis , is another example of a gut-derived component that may enter systemic circulation following a breach of the intestinal barrier and contribute to the pathogenesis of SLE (Patrick et al

Larger molecules and complexes, however, tumble more slowly in solution

Acknowledgements The authors gratefully acknowledge Lallemand Espaa for kindly supplying the yeast-derived products used in this study