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They proposed a microfluidic platform constituted of three regions in which patient-derived B-ALL cells from different subtypes, together with primary commercial HUVECs, mesenchymal stem cells (MSC) and osteoblasts, were seeded for mimicking the human cytological and histological complexity of bone marrow ( Figures 5A-C )

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In cells, H 2 O 2 serves as a critical signaling molecule capable of conveying redox rhythm signals to targets both in close proximity and at a distance

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Building upon the observed shifts in hepatic glucose handling and systemic substrate utilization, we next examined how GPR146 deficiency influences energy expenditure, revealing striking sex-specific differences

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