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10.1136/gutjnl-2015-310746 Gut 53 TadaH.NemotoE.ShimauchiH.WatanabeT.MikamiT.MatsumotoT.et al (2002)

Future work should focus on comparative efficacy studies between natural EGCG and its derivatives, optimization of synthesis methods for large-scale production, and investigation of potential side effects

Designed to gently even out darker patches on otherwise normal skin, from knees, elbows and underarms to neck, inner thighs and intimate areas

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Upon exceeding 150 CAG repeats, MSNs undergo progressive loss of neuronal characteristics while concurrently upregulating senescence-related and pro-apoptotic gene programs, culminating in neuronal degeneration

Neukomm et al, 2014) (Fig S1A) to measure transgenic reporter up-regulation for either of these pathways