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PSC Partners Seeking a Cure developed the international Our Voices survey to capture the presence, severity, and impact of PSC symptoms on quality of life

And with the world in its current state and the destruction of people and the planet, do we really want to witness more of this

10.1016/j.vph.2018.05.009 106 LiuM.GuoP.ZengM.ZhangY.JiaJ.LiuY.et al (2024b)

FEBS Lett 228:179181 Holan KR, Holzbach RT, Hermann RE, Cooperman AM, Claffey WJ (1979) Nucleation time: a key factor in the pathogenesis of cholesterol gallstone disease

The mitochondria are central to energy production in all cells and are affected by iron overload, leading to mitochondrial oxidative stress and participation in ferroptosis ( Recent studies have highlighted the role of mitochondrial calcium uniporters (MCU) in mediating iron-induced mitochondrial dysfunction

The first assumption is that A and Tau pathology are specific markers of Alzheimers disease