epithalon vs gdf11 GDF-11 Rather than a “rejuvenating” agent,

Rather than a rejuvenating agent, GDF11 may have a detrimental effect on liver senescence. Growth differentiation factor 11 accelerates liver senescence through the inhibition of autophagy [2021, open access] : r longevity GDF11 induces chemosensitization in human hepatocellular carcinoma cells by decreasing drug efflux transporters GDF11 Increases with Age and Inhibits Skeletal Muscle Regeneration: Cell Metabolism The versatility and paradox of GDF 11 ScienceDirect Restoring Systemic GDF11 Levels Reverses Age Related Dysfunction in Mouse Skeletal Muscle Science Systemic GDF11 attenuates depression like phenotype in aged mice via stimulation of neuronal autophagy Nature Aging

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