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Spitz DR, Adams DT, Sherman CM, Roberts RJ

In endothelial cells, factor Xa appears to exert its effects by docking to EPR-1, followed by cleavage and activation of protease-activated receptor 2 (PAR-2)

The novel assertion is if glutathione collapse occurs long before the first clinical PD symptom appears, then the neurotoxin-induced damage prior to symptoms is facilitated

This led us to focus on RNA-binding proteins (RBPs) that mainly bind to mRNA UTRs to regulate the processing, modification, stability and translation 39

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