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Jiang et al., 2023)

While our study highlights the significance of hepsin in the context of liver protection and its potential therapeutic implications in APAP-induced hepatotoxicity, there are limitations to consider when evaluating hepsin as a candidate drug or therapeutic strategy

References 1 MukherjeeMStoddartAGuptaRPNwaruBIFarrAHeavenMet al

Gastroenterology 135 , 13441357 (2008)

However, the delivery method is just as important as the tripeptide itself

Recently, a double blinded randomised controlled trial was published in which participants were administered either methyl-cobalamin or placebo for 6 weeks and then their treatment switched without washout for a further 6 weeks [64]