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Vercellini P, Somigliana E, Vigan P, Abbiati A, Daguati R, Crosignani PG

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Funding This work was supported by National Natural Science Foundation of China (82272549, 82472505, and 82472498)

Specifically, copper's ability to enhance MMP expression, particularly MMP-1, which regulates collagen breakdown, might lead to a temporary increase in cellular debris or a transient inflammatory response as the skin purges and rebuilds