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It prevents oxygen production, scavenges superoxide, and protects against lipid peroxidation in the plasma membrane []

These functions are critical for overall liver health and are essential for preventing liver diseases, such as fibrosis and cirrhosis, particularly in conditions like metabolic dysfunction-associated steatotic liver disease (MASLD).23 LSECs are also involved in the metabolism of various substances, including ethanol, through the expression of key enzymes such as ADH1 and CYP2E1.24 While much research has focused on the role of LSECs in MASLD, their involvement in ALD is less well understood and requires further exploration

Failure to account for environmental exposures may explain the lack of consistency

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Treasure Island, FL: StatPearls Publishing LLC

Adduct concentrations varied according to the degree of exposure