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[2] Use of estradiol cypionate injection is contraindicated in individuals with undiagnosed abnormal vaginal bleeding, known or suspected breast cancer or other estrogen-dependent neoplasia, active or prior venous thromboembolism, recent arterial thrombo-occlusive disease such as stroke or myocardial infarction, severe hepatic impairment, a history of hypersensitivity to estradiol or any excipients, and in those who are or may become pregnant

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Others are prescription-approved but lower in efficacy

Billing Guidelines for Full Reimbursement of CPT Code 20550 Healthcare providers should follow these billing guidelines to improve claim acceptance rate and get full reimbursement from Medicare and other commercial payers

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Alcohol has blood-thinning properties that can become a problem for certain people who take blood thinners, such as anticoagulants or antiplatelet agents