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Together with naringin, the use of poncirin from Poncirus trifoliata extract seems to exert antidepressant effects in mice by restoring vascular endothelial cell integrity in the hippocampus and controlling the neuroinflammatory responses of microglia at the Cornu Ammonis 1 (CA1) and dentate gyrus (DG) regions of the hippocampus [178]

This helps reduce the risk of side effects

This has been shown to support this guthormonemetabolism axis 17,18 in several ways: Clinical research shows that B

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