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The resulting accumulation of cholesterol induces T-cell exhaustion ( Spatial analysis of immune cells in triple-negative breast cancer identified distinct meta-signatures based on CD8 + T-cell localization

However, minor leakage may occur during treatment, which could cause small sores

Genome-scale metabolic modelling of hepatocytes reveals serine deficiency in patients with non-alcoholic fatty liver disease

Sacco S, Ricci S, Degan D, Carolei A

doi: 10.3390/mi14091740 113 SalzerHJFPrattesJFlickHReimannMHeyckendorfJKalsdorfBet al

In the present study, the involvement of ROS in the induction of autophagy by glucose starvation was not investigated but our data confirm the involvement of ERK1/2, which may also modulate autophagy induced by amino acid deprivation in the human colonic cell line HT-29 (Ogier-Denis et al