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Third, clinical efforts should include establishing multicenter FRDA biobanks to validate associations between ferroptosis biomarkers (such as ACSL4 and mitochondrial iron content) and clinical measures including SARA ataxia scores and left ventricular ejection fraction, and conducting combination trials of ferroptosis inhibitors with ironsulfur cluster metabolism regulators to evaluate synergistic improvement in neurologic and cardiac function

Global status report on the public health response to dementia (PDF)

doi: 10.1371/journal.pone.0219987 150

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In a 1995 TV commercial for Pepcid AC, the narrator encourages, Take Pepcid AC before dinner, and you can stop heartburn before it starts

Product Facts Supplement Facts Serving Size 6 Veg Capsules Servings Per Container 20 ** Percent Daily Values are based on a 2,000 calorie diet