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Pre-treatment with sesamol (10 mg/kg, i.p.) markedly enhanced body weight, locomotor activity, and diminished oxidative damage by decreasing lipid peroxidation (LPO) while elevating catalase (CAT) and superoxide dismutase (SOD) levels in rat brains, thereby presenting a potentially viable strategy for the management of HD (Lum et al

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However, there are some intriguing varia- tions in organisms such as halobacteria, in which GSH can be replaced by other sulphur compounds like g- glutamylcysteine (g-EC) and thiosulphate (Newton & Javor 1985)

A CIC target binding octamer sequence occurs in the promoter regions of the folate transport genes FR, PCFT, and RFC1, and dihydrofolate reductase, and binding was confirmed by chromatin immunoprecipitation assays

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Reduced and bioavailable forms: Supply glutathione in its active, reduced state, allowing cells to utilise it immediately without additional metabolic conversion (NIH)