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Author Contributions All authors meet the International Committee of Medical Journal Editors (ICJME) criteria for authorship for this article, take responsibility for the integrity of the work as a whole, and have given their approval for this version to be published

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Agitation after reconstitution is necessary to ensure complete dissolution, but vigorous shaking denatures peptides through shear stress

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Likewise, in the rats with the occluded superior mesenteric vein and artery, we noted an increase in the liver and spleen relative weight, which was markedly counteracted after BPC 157 therapy (Figure 3)

Together, evidence supports the role of time of day alterations in the efficacy of tPA and hemorrhagic transformation, as a potential negative consequence of tPA administration