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Youre feeling strong and energetic, thinking clearly, feeling upbeat, and then gradually, maybe over the course of several months or even years, you begin to notice that youve lost the pep in your step

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When there are too many of these, they are in the wrong place, or they have changed in some way the immune system can go haywire and attack healthy cells

During acute exacerbations, it has been shown that mucus from patients with cystic fibrosis demonstrates increases in elastic and viscous moduli, but these measurements return to baseline once the exacerbation has been treated [106]

In some embodiments, the immunotherapy can be CAR (chimeric antigen receptor) -T therapy, wherein T cells are engineered to express a CAR comprising an antigen binding domain specific for an antigen on a tumor cell of interest

Studies also demonstrate reduced fibrosis and improved functional recovery post-injury